A Study on Spermatogenesis in Male Renal Transplant Recipients Receiving Valganciclovir (Valcyte®) Versus Untreated Matched Controls

Summary

This observational study will compare spermatogenesis in male adult renal transplant recipients receiving valganciclovir versus untreated matched controls. Data will be collected from each participant for up to 52 weeks post transplant.

Timeline

Start

2012-01-30

Primary completion

2015-09-29

Completion

2016-12-30

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Cohort A: Partcipants Who Received Valganciclovir vs Cohort B: Untreated Participants; p = 0.0075; Mean Difference -40.166 (95% CI -68.869 to -11.463); Mixed Models Analysis NCT01663740 ↗

Drugs

Indications