drugset / Trial / NCT01665638
Effects of Canagliflozin on C-peptide Clearance in Healthy Volunteers
RandomizedCrossoverTriple-blind
Summary
The purpose of this study is to assess whether treatment with a single oral 300 mg dose of canagliflozin alters the kinetics (ie, clearance/removal from body) of serum C-peptide (a protein released from the pancreas during insulin secretion) in healthy adult volunteers.
Timeline
- Start
- 2012-09
- Primary completion
- 2012-10
- Completion
- 2012-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CANAGLIFLOZIN ANHYDROUS | Small molecule | 300 mg | Oral |
| Background | HUMAN C-PEPTIDE | Peptide | 150 ug | Intravenous |
| Background | Somatostatin | Traditional medicine (herbal / TCM) | 500 ug | Intravenous |
Indications
No indication recorded.