drugset / Trial / NCT01667107

A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105)

NCT01667107

Phase 4 Terminated 26 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelPrevention

Summary

This single site study will examine plasma and alveolar compartment (AC) levels of posaconazole in cystic fibrosis (CF) and non-cystic fibrosis (non-CF) lung transplant recipients receiving routine post-operative anti-fungal prophylaxis. Invasive fungal infection rates will be assessed following transplantation.

Timeline

Start
2013-01-23
Primary completion
2014-01-16
Completion
2014-01-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Posaconazole Small molecule 200 mg Oral
Subject Posaconazole Small molecule 400 mg Oral