drugset / Trial / NCT01667107
A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105)
Non-randomizedParallel-groupOpen-labelPrevention
Summary
This single site study will examine plasma and alveolar compartment (AC) levels of posaconazole in cystic fibrosis (CF) and non-cystic fibrosis (non-CF) lung transplant recipients receiving routine post-operative anti-fungal prophylaxis. Invasive fungal infection rates will be assessed following transplantation.
Timeline
- Start
- 2013-01-23
- Primary completion
- 2014-01-16
- Completion
- 2014-01-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Posaconazole | Small molecule | 200 mg | Oral |
| Subject | Posaconazole | Small molecule | 400 mg | Oral |