The Effects of Nebivolol on the NO-system in Patients With Essential Hypertension

Summary

Investigators want investigate the following hypothesis: 1. Nebivolol increases nitric oxide activity in the systemic circulation and the kidney 2. The increased activity of nitric oxide during nebivolol treatment can be demonstrated by inhibition of NO synthesis with L-NMMA. We expect increased responses in blood pressure and sodium excretion is expected during nebivolol treatment compared to placebo.

Timeline

Start

2012-08

Primary completion

2013-09

Completion

2013-09

Drugs

Indications