drugset / Trial / NCT01682031
Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy
Phase 2
Terminated
18 enrolled
Roswell Park Cancer Institute
National Cancer Institute (NCI) · collab
RandomizedParallel-groupDouble-blindSupportive care
Summary
This randomized phase II trial is studying how well selenomethionine (SLM) works in reducing mucositis in patients with locally advanced head and neck cancer who are receiving cisplatin and radiation therapy. SLM may help prevent or reduce mucositis, or mouth sores, in patients receiving chemotherapy and radiation therapy. It is not yet known whether SLM is more effective than a placebo in reducing mucositis
Timeline
- Start
- 2009-06
- Primary completion
- 2012-04
- Completion
- 2012-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | Intravenous |
| Subject | Selenomethionine | Other / unclassified | — | Oral |
Indications
chemotherapy-induced toxicity
hypopharynx squamous cell carcinoma
laryngeal squamous cell carcinoma
lip and oral cavity squamous cell carcinoma
mucositis
nasal cavity and paranasal sinus squamous cell carcinoma
nasopharyngeal squamous cell carcinoma
oropharynx squamous cell carcinoma
radiation-induced disorder