drugset / Trial / NCT01682187
A Dose-Escalation Study in Participants With Recurrent Malignant Glioma
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a study of oral LY2157299 as monotherapy and in combination with lomustine in participants with recurrent malignant glioma.
Timeline
- Start
- 2005-12-15
- Primary completion
- 2012-05-22
- Completion
- 2024-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Galunisertib | Small molecule | 40 mg | Oral |
| Subject | Galunisertib | Small molecule | 80 mg | Oral |
| Subject | Galunisertib | Small molecule | 150 mg | Oral |
| Subject | Galunisertib | Small molecule | 360 mg | Oral |
| Subject | Lomustine | Small molecule | — | Oral |