drugset / Trial / NCT01682499
Calcium and Magnesium Infusion for the Prevention of Taxane Induced Neuropathy
Phase 1
Completed
50 enrolled
Beth Israel Medical Center
St. Luke's-Roosevelt Hospital Center · collab
NaSingle-groupOpen-labelPrevention
Summary
This is a pilot study evaluating the feasibility of intravenous calcium and magnesium (Ca/Mg) infusion for prevention of taxane induced neuropathy in patients with early stage breast cancer receiving adjuvant or neo-adjuvant paclitaxel, either given every 2 weeks for 4 cycles or every week for 12 weeks.
Timeline
- Start
- 2012-08
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Magnesium Sulfate | Other / unclassified | 1 g | Intravenous |
| Subject | calcium gluconate | Small molecule | 1 g | Intravenous |