Pharmacokinetic Study of Fluconazole in Premature Infants

Phase 2 Completed 80 enrolled Seoul National University Hospital

Non-randomizedParallel-groupOpen-labelBasic science

Summary

The purpose of this study is to investigate the pharmacokinetics of fluconazole which is used as prophylaxis of invasive fungal infection in premature infants.

Timeline

Start: 2012-09
Primary completion: 2014-10
Completion: 2014-10

Publications

Kim YK, Lee J, Oh J, Rhee SJ, Shin SH, Yoon SH, Lee S, Kim HS, Yu KS. Population Pharmacokinetic Study of Prophylactic Fluconazole in Preterm Infants for Prevention of Invasive Candidiasis. Antimicrob Agents Chemother. 2019 May 24;63(6):e01960-18. doi: 10.1128/AAC.01960-18. Print 2019 Jun.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fluconazole	Small molecule	3 mg/kg	Intravenous

Indications

No indication recorded.