Parathyroid Hormone for the Treatment of Humerus Fractures

Phase 4 Unknown 72 enrolled Hvidovre University Hospital Takeda · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Hypothesis: The investigators want to study whether parathyroid hormone improves healing of humerus after a fracture. The investigators will assess healing of the humerus with Constant score.

Timeline

Start: 2012-03
Primary completion: 2012-12
Completion: 2013-12

Publications

Background Aspenberg P, Genant HK, Johansson T, Nino AJ, See K, Krohn K, Garcia-Hernandez PA, Recknor CP, Einhorn TA, Dalsky GP, Mitlak BH, Fierlinger A, Lakshmanan MC. Teriparatide for acceleration of fracture repair in humans: a prospective, randomized, double-blind study of 102 postmenopausal women with distal radial fractures. J Bone Miner Res. 2010 Feb;25(2):404-14. doi: 10.1359/jbmr.090731.
Background Peichl P, Holzer LA, Maier R, Holzer G. Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women. J Bone Joint Surg Am. 2011 Sep 7;93(17):1583-7. doi: 10.2106/JBJS.J.01379.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	1-84 parathyroid hormone	Unknown	100 ug	Subcutaneous

Indications

No indication recorded.