A Study of Implantation of Retinal Pigment Epithelium in Subjects with Acute Wet Age Related Macular Degeneration

Phase 1 Completed 9 enrolled Moorfields Eye Hospital NHS Foundation Trust University College, London · collab

NaSingle-groupOpen-labelTreatment

Summary

Phase 1 trial of retinal pigment epithelium replacement in subjects with wet age-related macular degeneration in whom there is rapidly progressing vision loss

Timeline

Start: 2021-10-14
Primary completion: 2023-10-10
Completion: 2024-06-24

Publications

Soomro T, Georgiadis O, Coffey PJ, da Cruz L. Safety, structure and function five years after hESC-RPE patch transplantation in acute neovascular AMD with submacular haemorrhage. Graefes Arch Clin Exp Ophthalmol. 2024 Sep;262(9):3057-3060. doi: 10.1007/s00417-024-06463-4. Epub 2024 Apr 5. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	PF-05206388	Cell therapy	—	Other

A Study of Implantation of Retinal Pigment Epithelium in Subjects with Acute Wet Age Related Macular Degeneration

Summary

Timeline

Publications

Drugs

Indications