drugset / Trial / NCT01694004
Nutrient Sensing in the Duodenum
Phase 1
Completed
16 enrolled
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
NaSingle-groupOpen-labelBasic science
Summary
Preliminary studies in humans suggest that the presence of lipids in the gut can modify glucose absorption. The overall hypothesis of this proposal is that long chain fatty acid sensing in the duodenum has a significant role in modifying nutrient (glucose and amino acid) absorption from the GI tract through a gut-brain-gut axis.
Timeline
- Start
- 2012-11
- Primary completion
- 2014-10-27
- Completion
- 2014-10-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Benzocaine | Small molecule | — | Other |