Functional Applications of Hyperpolarized 129Xe MRI

Summary

The overall objectives of our study are to determine the capabilities of hyperpolarized 129Xe MRI to measure lung function and its potential to sensitively detect pulmonary disease and its progression in COPD. We hypothesize that measurement of alveolar surface area, septal thickness, and capillary transit time measured with hyperpolarized 129Xe will correlate better with quality of life measures in COPD subjects than traditional diagnostic measures such as spirometry and Computed Tomography.

Timeline

Start

2013-01

Primary completion

2016-12

Completion

2016-12

Outcome

Outcome not reported

Stopped (Business): “Funding ended prior to resolution of all equipment (polarizer) issues.”

Drugs

Indications