drugset / Trial / NCT01701089

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers

NCT01701089

Phase 1 Completed 17 enrolled Hoffmann-La Roche
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This open-label, multiple dose, parallel group study will assess the monoamine oxidase in the brain by in vivo positron emission tomography (PET) and safety of RO4602522 in patients with Alzheimer disease and in healthy volunteers. Patients and volunteers will receive multiple doses of RO4602522 and up to three injections of C11-L-deprenyl-D2 used in the PET.

Timeline

Start
2012-09
Primary completion
2013-05
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject RO4602522 Unknown
Background 11C-L-deprenyl-D2 Unknown Intravenous

Indications