drugset / Trial / NCT01704638
Kinetics of Fluvoxamine and Digoxin in Subjects With Different MDR1 Genotypes
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The investigators will compare plasma kinetics of two marker drugs in individuals with different genetic variations in the MDR1-gene. The hypothesis is that one group will have higher exposure than the other.
Timeline
- Start
- 2008-08
- Primary completion
- 2012-10
- Completion
- 2012-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | — | — |
| Subject | Fluvoxamine | Unknown | — | — |