drugset / Trial / NCT01707082
A Study To Test The Safety, Amount And Effects Of PF-06282999 In Healthy Overweight Adults And A Study To Test The Effects Of PF-06282999 On The Amount Of The Approved Drug, Midazolam, In Healthy Adults
RandomizedParallel-groupDouble-blindBasic science
Summary
Part A of the study will test the safety, the amount of drug in the body, and effects of the drug in the body after multiple doses. This will be conducted in healthy overweight adults. Part B of the study will test the effects of multiple doses of the investigational drug on the amount of midazolam, an approved drug, in healthy adults.
Timeline
- Start
- 2012-10
- Primary completion
- 2013-05
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Midazolam | Small molecule | 7.5 mg | — |
| Subject | PF-06282999 | Small molecule | 10 mg | — |
| Subject | PF-06282999 | Small molecule | 30 mg | — |
| Subject | PF-06282999 | Small molecule | 100 mg | — |
| Subject | PF-06282999 | Small molecule | 250 mg | — |
| Subject | PF-06282999 | Small molecule | 350 mg | — |
| Subject | PF-06282999 | Small molecule | 500 mg | — |
Indications
No indication recorded.