drugset / Trial / NCT01707420

Preoperative Gabapentin for Post-tonsillectomy Pain in Children

NCT01707420

Completed 36 enrolled University of Colorado, Denver
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The typical post-operative course for children following surgical removal of their tonsils and adenoids can be challenging, especially for pain control. First line medications for pain include intravenous and enteral narcotics, acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) or N-methyl-D-aspartate (NMDA) antagonists but their effects appear to be short-lived. Gabapentin has been shown in adult studies to tone down the body's response to pain and decreases opioid use post-operatively. The purpose of this study is to see if a single preoperative dose will reduce post-operative pain scores and the amount of analgesic used.

Timeline

Start
2012-08
Primary completion
2015-12
Completion
2015-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gabapentin Small molecule 20 mg/kg Oral

Indications

No indication recorded.