drugset / Trial / NCT01710033

A Study Of CP-690,550 In Stable Kidney Transplant Patients

NCT01710033

Phase 1 Completed 28 enrolled Pfizer
RandomizedParallel-groupDouble-blindBasic science

Summary

This was a Phase 1 dose escalation study to evaluate the safety, tolerability and pharmacokinetics of 28-day treatment of CP-690,550 in stable renal allograft recipients. In Stage 1, ascending doses of CP-690,550 were to be administered sequentially to 3-4 cohorts of subjects. After Stage 1, one dose level was to be selected for dosing in an expanded cohort in Stage 2.

Timeline

Start
2003-09
Primary completion
2005-04
Completion
2005-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Tofacitinib Small molecule 5 mg
Subject Tofacitinib Small molecule 15 mg
Subject Tofacitinib Small molecule 30 mg

Indications

No indication recorded.