Quantitative 18F-AV-133 PET Imaging in Subjects With Diabetes and Healthy Controls

Summary

To evaluate 18F-AV-133 imaging of the pancreas in patients with early type 2 diabetes, late type 2 diabetes, subjects with pre-diabetes and in healthy overweight/obese control subjects. These subjects will also be evaluated for beta-cell function as measured by the insulin and C-peptide response to a challenge with intravenous arginine under basal and glucose enhanced conditions.

Timeline

Start

2012-12

Primary completion

2015-09

Completion

2015-09

Drugs

Indications