drugset / Trial / NCT01716338
Glyburide Healthy Volunteer Study
Phase 1
Completed
21 enrolled
Washington University School of Medicine
United States Department of Defense · collabUniversity of Maryland · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Glyburide is a medication that has been safely used for several decades to treat non-insulin dependent diabetes. This pilot study seeks to evaluate whether glyburide, administered at the lowest dose (1.5 mg/dL daily) to healthy (non-diabetic) subjects is safe both physically and cognitively. The investigators are hopeful that the results of this study will provide the necessary foundation to evaluate this medication's use on a larger scale to determine the feasibility of using glyburide in soldiers either prophylactically or for the treatment of brain injury.
Timeline
- Start
- 2013-01
- Primary completion
- 2014-05
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Glyburide | Small molecule | 1.5 mg | Oral |
Indications
No indication recorded.