drugset / Trial / NCT01719952

Haemodynamic and Cardiovascular Effects of Carbetocin and Oxytocin

NCT01719952

RandomizedParallel-groupQuadruple-blindTreatment

Summary

A double-blinded randomised control trial conducted in the Department of Obstetrics and Gynaecology of a tertiary hospital, Universiti Kebangsaan Malaysia Medical Centre (UKMMC) for two years duration from January 1st, 2012 till December 31st, 2013. The aim of the study is to compare the haemodynamic and cardiovascular effects between intravenous carbetocin 100 μg and intravenous oxytocin 5 IU in women undergoing elective Lower Segment Caesarean Section (EL LSCS). Study hypothesis: A single injection of carbetocin is haemodynamically and cardiovascularly safe and has similar efficacy in comparison to a single injection of oxytocin.

Timeline

Start
2012-01
Primary completion
2013-12
Completion
2014-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carbetocin Peptide 100 ug Intravenous
Comparator Oxytocin Peptide 5 iu Intravenous

Indications