drugset / Trial / NCT01719952
Haemodynamic and Cardiovascular Effects of Carbetocin and Oxytocin
RandomizedParallel-groupQuadruple-blindTreatment
Summary
A double-blinded randomised control trial conducted in the Department of Obstetrics and Gynaecology of a tertiary hospital, Universiti Kebangsaan Malaysia Medical Centre (UKMMC) for two years duration from January 1st, 2012 till December 31st, 2013. The aim of the study is to compare the haemodynamic and cardiovascular effects between intravenous carbetocin 100 μg and intravenous oxytocin 5 IU in women undergoing elective Lower Segment Caesarean Section (EL LSCS). Study hypothesis: A single injection of carbetocin is haemodynamically and cardiovascularly safe and has similar efficacy in comparison to a single injection of oxytocin.
Timeline
- Start
- 2012-01
- Primary completion
- 2013-12
- Completion
- 2014-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carbetocin | Peptide | 100 ug | Intravenous |
| Comparator | Oxytocin | Peptide | 5 iu | Intravenous |