drugset / Trial / NCT01723826

A Long-Term Safety Extension of Studies ABE4869g and ABE4955g in Participants With Mild to Moderate Alzheimer's Disease Treated With Crenezumab

NCT01723826 ↗

Phase 2 Completed 360 enrolled Genentech, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This Phase II, open-label extension (OLE), multicenter study will evaluate the long-term safety and tolerability of crenezumab in participants with mild to moderate Alzheimer's disease who have participated in and completed the treatment period of the Phase II Study ABE4869g (NCT01343966) or ABE4955g (NCT01397578). Participants who received placebo in Study ABE4869g (NCT01343966) or ABE4955g (NCT01397578) will receive crenezumab. Anticipated time on study treatment is 144 weeks.

Timeline

Start
2012-12-07
Primary completion
2017-02-08
Completion
2017-02-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Crenezumab Monoclonal antibody — Intravenous

Indications