The Role of Antidepressants or Antipsychotics in Preventing Psychosis

Summary

This is a randomized, controlled pilot study comparing the antidepressant fluoxetine with the second generation antipsychotic aripiprazole in approximately 10 subjects aged 12-25 at risk for developing psychosis. Our primary hypotheses are that compared to aripiprazole, fluoxetine will be better tolerated and will lead to greater improvement in symptoms at the end of 6 months of treatment.

Timeline

Start

2012-10

Primary completion

2014-05

Completion

2014-05

Drugs

Indications