drugset / Trial / NCT01727089
Bevacizumab With or Without TRC105 in Treating Patients With Metastatic Kidney Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
This randomized phase II trial studies how well bevacizumab with or without anti-endoglin monoclonal antibody TRC105 (TRC105) works in treating patients with kidney cancer that has spread to other parts of the body (metastatic). Monoclonal antibodies, such as bevacizumab and anti-endoglin monoclonal antibody TRC105, may block tumor growth in different ways by targeting certain cells.
Timeline
- Start
- 2012-11-01
- Primary completion
- 2017-08-08
- Completion
- 2017-08-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | — | Intravenous |
| Subject | Carotuximab | Monoclonal antibody | — | Intravenous |