drugset / Trial / NCT01727531

IDO2 Genetic Status Informs the Neoadjuvant Efficacy of Chloroquine (CQ) in Brain Metastasis Radiotherapy

NCT01727531

Completed 20 enrolled Main Line Health
NaSingle-groupOpen-labelTreatment

Summary

This research is being done to determine if a short course of Chloroquine (five weeks) before, during and after whole brain radiation therapy (WBRT) will improve the overall survival of subjects being treated for brain metastases.

Timeline

Start
2008-12
Primary completion
2013-08
Completion
2013-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Chloroquine Small molecule 250 mg Oral