drugset / Trial / NCT01730352
Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients
Phase 2/3
Completed
100 enrolled
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to determine whether eradication of Helicobacter pylori infection is effective in the improvement of platelet counts in children and adolescents with chronic ITP.
Timeline
- Start
- 2008-10
- Primary completion
- 2011-05
- Completion
- 2012-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | 50 mg/kg | Oral |
| Subject | Amoxicillin | Other / unclassified | 500 mg | Oral |
| Subject | Clarithromycin | Small molecule | 15 mg/kg | Oral |
| Subject | Clarithromycin | Small molecule | 500 mg | Oral |
| Subject | Doxycycline | Small molecule | 4.4 mg/kg | Oral |
| Subject | Doxycycline | Small molecule | 100 mg | Oral |
| Subject | Furazolidone | Small molecule | 7 mg/kg | Oral |
| Subject | Furazolidone | Small molecule | 200 mg | Oral |