drugset / Trial / NCT01737671
Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to learn if it is safe to receive methotrexate through the fourth ventricle of the brain in patients with brain tumors. Methotrexate is designed to block cancer cells from dividing, which may slow or stop their growth and spread throughout the body. This may cause the cancer cells to die.
Timeline
- Start
- 2012-12-27
- Primary completion
- 2018-01-11
- Completion
- 2018-01-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methotrexate | Small molecule | 2 mg | Other |
| Background | Leucovorin | Small molecule | 5 mg/m2 | Intravenous |