drugset / Trial / NCT01737671

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

NCT01737671

Phase 0 Completed 7 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if it is safe to receive methotrexate through the fourth ventricle of the brain in patients with brain tumors. Methotrexate is designed to block cancer cells from dividing, which may slow or stop their growth and spread throughout the body. This may cause the cancer cells to die.

Timeline

Start
2012-12-27
Primary completion
2018-01-11
Completion
2018-01-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Methotrexate Small molecule 2 mg Other
Background Leucovorin Small molecule 5 mg/m2 Intravenous