drugset / Trial / NCT01740492

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

NCT01740492

Phase 1 Completed 75 enrolled Rhode Island Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

This study aims to address both the management and evaluation of pain. The primary aim of this study is to determine the efficacy of low dose ketamine in adults with moderate to severe pain in the emergency department as compared with parenteral opioids alone. Another aim is to examine the safety of low dose ketamine compared to opioids alone. The investigators hypothesize that low dose ketamine will result in more effective pain control than morphine alone and will not be associated with an increase in adverse events.

Timeline

Start
2012-09
Primary completion
2014-06
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.15 mg/kg Intravenous
Subject Ketamine Small molecule 0.3 mg/kg Intravenous

Indications

No indication recorded.