drugset / Trial / NCT01743118

Antipsoriatic Effect of a Topical Formulation for the Treatment of Psoriasis Vulgaris

NCT01743118

Phase 1 Completed 24 enrolled Circassia Limited Bioskin GmbH · collab
NaSingle-groupSingle-blindTreatment

Summary

The current most important topical treatments for psoriasis are vitamin D3 analogues and/or corticosteroids. The possibility of another effective treatment for psoriasis could be based on the immunosuppressive efficacy of selective blockers of a lymphocyte potassium channel. The aim of the clinical trial is to evaluate the safety, tolerability and anti-psoriatic efficacy of topical SPS4251 formulations in comparison to placebo and to a marketed topical Vitamin-D analogue ointment in a psoriasis plaque test.

Timeline

Start
2013-03
Primary completion
2013-07
Completion
2013-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Calcipotriol Small molecule Topical
Subject SPS4251 Unknown 0.01 % Topical
Subject SPS4251 Unknown 0.1 % Topical
Subject SPS4251 Unknown 1 % Topical

Indications