drugset / Trial / NCT01745055
Co-Administration Of Methotrexate And CP-690,550
Non-randomizedSingle-groupOpen-labelBasic science
Summary
This study was designed to estimate the effects of methotrexate (MTX) on the pharmacokinetics (PK) of CP-690,550 when administered to subjects with rheumatoid arthritis (RA), to estimate the effects of CP-690,550 on the PK of MTX and to evaluate the short-term safety and tolerability of co-administration of CP-690,550 and MTX.
Timeline
- Start
- 2005-04
- Primary completion
- 2006-06
- Completion
- 2006-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methotrexate | Small molecule | — | Oral |
| Subject | Tofacitinib | Small molecule | 30 mg | Oral |