drugset / Trial / NCT01749085
Study To Determine The Effect Of Food And Strong CYP3A4 Enzyme Inhibitor On PF-04449913 Drug Levels
Non-randomizedCrossoverOpen-labelBasic science
Summary
The study aims to determine what effect a high fat meal will have on the drug exposure of PF-04449913. The study also aims to determine the effect of a strong enzyme (CYP3A4) inhibitor on drug exposure of PF-04449913.
Timeline
- Start
- 2012-12
- Primary completion
- 2013-02
- Completion
- 2013-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glasdegib | Small molecule | 200 mg | Oral |
| Background | Ketoconazole | Small molecule | — | — |
Indications
No indication recorded.