drugset / Trial / NCT01749137

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

NCT01749137

Phase 2 Completed 74 enrolled Rhythm Pharmaceuticals, Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the effects of RM-493 on mean percent body weight loss, and other weight loss parameters as well as Pharmacokinetic (PK) profile, and ambulatory blood pressure in obese participants. The study is designed to evaluate the efficacy and tolerability of a single dose of RM-493. The study drug (RM-493 and placebo) will be administered subcutaneously in a blinded fashion.

Timeline

Start
2013-01-14
Primary completion
2013-09-28
Completion
2013-09-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Setmelanotide Protein / enzyme biologic 1 mg Subcutaneous

Indications