A Study to Assess the Effect of SB 659032 on Platelet Function

Summary

This will be an open-label, single dose, single period study. Approximately 14 subjects will receive one dose of 250 mg of non-enteric coated SB-659032 following a low-fat breakfast. This study will evaluate whether SB-659032 has an effect on platelet function as determined by platelet aggregation tests using the agonists ADP and collagen. Blood samples for PK analysis and measurement of Lp-PLA2 activity will also be collected

Timeline

Start

2004-09

Primary completion

2004-11

Completion

2004-11

Drugs

Indications