drugset / Trial / NCT01750983

Ipilimumab and Lenalidomide in Advanced Cancer

NCT01750983 ↗

Phase 1 Completed 101 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to find the highest tolerable dose of the combination of Yervoy® (ipilimumab) with Revlimid® (lenalidomide) that can be given to patients with advanced cancer. The safety of these drugs will also be studied. Ipilimumab is designed to increase the immune system's ability to fight cancer. Lenalidomide is designed to change the body's immune system. It may also interfere with the development of tiny blood vessels that help support tumor growth. This may decrease the growth of cancer cells.

Timeline

Start
2013-03
Primary completion
2019-02-21
Completion
2019-02-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody 1.5 mg Intravenous
Subject Lenalidomide Other / unclassified 10 mg Oral