drugset / Trial / NCT01761773

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

NCT01761773

Phase 1 Completed 32 enrolled Exelixis
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The main objective of the trial is to compare the pharmacokinetics of a 60 mg dose of cabozantinib in adult subjects with impaired renal function compared with healthy adult subjects. Another objective is to assess the safety and tolerability of cabozantinib in these adult subjects.

Timeline

Start
2012-12
Primary completion
2013-04
Completion
2014-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 60 mg Oral