Oxidant Status and Effect of Antioxidant in Immune Thrombocytopenia

Summary

Oxidative stress occurs as a result of increased activity of free radical-producing enzymes, decreased activity of free radical-removing enzymes, and insufficient levels of antioxidants. The most sensitive molecules to oxidation are lipids. Loss of cell membrane elasticity, increased cell fragility, and a shortened cellular life span results from oxidation of cell membrane lipids.

Timeline

Start

2013-03

Primary completion

2013-09

Completion

2013-09

Drugs

Indications