drugset / Trial / NCT01767259
Pharmacokinetic Interactions of Valsartan and Hydrochlorothiazide
RandomizedCrossoverOpen-label
Summary
This study was conducted to compare the rate and extent of absorption of valsartan and hydrochlorothiazide following oral administration as a fixed dose combination tablet and concomitant administration of the individual drugs under fasting conditions in healthy Egyptian subjects. The study was extended to investigate any potential reaction between VAL and HCT.
Timeline
- Start
- 2012-10
- Primary completion
- 2012-12
- Completion
- 2012-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydrochlorothiazide | Unknown | 12.5 mg | Oral |
| Subject | Hydrochlorothiazide | Unknown | 25 mg | Oral |
| Subject | Valsartan | Small molecule | 160 mg | Oral |
| Subject | Valsartan | Small molecule | 320 mg | Oral |
Indications
No indication recorded.