drugset / Trial / NCT01773538
Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement
Completed
136 enrolled
Mette Munk Lauridsen
Esbjerg Hospital - University Hospital of Southern Denmark · collabOdense University Hospital · collabRegion of Southern Denmark · collab
RandomizedParallel-groupDouble-blindDiagnostic
Summary
The investigators wish to investigate how the Continuous Reaction Time (CRT) method can be used in the diagnosis and monitoring of covert hepatic encephalopathy (cHE)in patients with cirrhosis of the liver. The hypothesis is that the CRT method (duration 10-2 minutes) can serve as a tool in the diagnosis and monitoring of cHE and is an alternative to using the Portosystemic Encephalopathy Test (PSE)(duration 20-25 minutes).
Timeline
- Start
- 2013-01
- Primary completion
- 2015-10
- Completion
- 2015-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Branched-Chain Amino Acids | Other / unclassified | 30 g | — |
| Comparator | Lactulose | Other / unclassified | 25 ml | — |
| Comparator | Rifaximin | Other / unclassified | 550 mg | — |