Milnacipran for Lumbosacral Radicular Pain

Summary

This study investigates whether milnacipran reduces radicular pain ("sciatica") in patients with lumbosacral disc disease.

Timeline

Start

2010-03

Primary completion

2011-10

Completion

2011-10

Outcome

Met primary endpoint

paper Milnacipran treatment yielded statistically significant reduction in radicular pain (VAS-Rad, P = .01) PMID 25664215 ↗

Publications

• Marks DM, Pae CU, Patkar AA. A double-blind, placebo-controlled, parallel-group pilot study of milnacipran for chronic radicular pain (sciatica) associated with lumbosacral disc disease. Prim Care Companion CNS Disord. 2014 Aug 14;16(4):10.4088/PCC.14m01658. doi: 10.4088/PCC.14m01658. eCollection 2014.

Drugs

Indications