drugset / Trial / NCT01780220

Radiotherapy Plus Hormone Therapy in Biochemically-relapsing Prostate Cancer Patients Following Surgery

NCT01780220

Phase 1/2 Completed 47 enrolled UNICANCER
NaSingle-groupOpen-labelTreatment

Summary

As there is no prospective data on the combination of abiraterone and salvage radiotherapy, the aim of this study is to further evaluate the safety profile of abiraterone acetate plus prednisone in patients with prostate cancer who are biochemically relapsing after surgery and undergo salvage radiotherapy with 6-months LH-RH agonist. The investigators hypothesize that the toxicity profile of both treatments should not potentiate each other. This study will also provide preliminary data on the efficacy of this combination.

Timeline

Start
2012-12
Primary completion
2022-01-07
Completion
2022-01-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Abiraterone acetate Small molecule 1000 mg
Background Prednisone Other / unclassified 10 mg