drugset / Trial / NCT01782027

Mendelian Reverse Cholesterol Transport Study

NCT01782027 ↗

Terminated 17 enrolled University of Pennsylvania
NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to investigate the use of radiolabeled particulate cholesterol administered intravenously in association with albumin, as a method to study reverse cholesterol transport (RCT) in people carrying mutations in genes known to affect high density lipoprotein (HDL) metabolism by analyzing changes in the tracer activity in total plasma, lipoproteins fractions and feces.

Timeline

Start
2012-10
Primary completion
2024-09-04
Completion
2024-09-04

Outcome

Outcome not reported

Stopped (Business): “Lack of funding”

Drugs

EvaluationDrugModalityDoseRoute
Subject 3H-cholesterol Unknown 100 unknown Intravenous