drugset / Trial / NCT01784211

A Study of LY2605541 and Glargine and Exercise in Participants With Type 1 Diabetes

NCT01784211

Phase 1 Completed 76 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelBasic science

Summary

The purpose of this study is to measure how much of the study drug or insulin glargine gets into the blood stream and how long it takes the body to get rid of it. The effect of exercise will also be evaluated. This study has two parts. In Part A, each participant will receive a daily injection of LY2605541 or insulin glargine for about 15 days. Some participants may continue into Part B. In Part B, participants will receive a daily injection of LY2605541 or insulin glargine with or without exercise. Part B lasts about 6 days. Participants will remain on their regular physician-prescribed mealtime insulin throughout the study.

Timeline

Start
2013-02
Primary completion
2013-11
Completion
2013-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Insulin Peglispro Protein / enzyme biologic 0.5 iu/kg Subcutaneous
Comparator insulin glargine Protein / enzyme biologic 0.5 iu/kg Subcutaneous