drugset / Trial / NCT01784666

Adjunctive Isradipine for the Treatment of Bipolar Depression

NCT01784666

Phase 2 Terminated 2 enrolled Massachusetts General Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

This study investigates the medication isradipine, which is currently approved by the FDA to treat high blood pressure, in the treatment of depression in bipolar disorder. Isradipine or placebo (contains no active medication) will be used as an "add-on" to lithium, valproate, and/or atypical antipsychotics for individuals currently experiencing a major depressive episode. Our hypothesis is that isradipine will be superior to placebo in improving depressive symptoms.

Timeline

Start
2013-02
Primary completion
2014-04
Completion
2014-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Isradipine Small molecule

Indications