Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test

Summary

The purpose of this study is to investigate safety and efficacy of intravenously injected 0.4% 13-C-Methacetin solution for the determination of liver function with the LiMAx-test on patients with partial liver resection. The LiMAx-test is compared with an untreated control group and post-surgical management of both groups is investigated.

Timeline

Start

2013-01

Primary completion

2015-09

Completion

2015-09

Outcome

Met primary endpoint

paper Thirty-six of 58 patients (62 per cent) in the LiMAx® group were transferred directly to a general ward, compared with one of 60 (2 per cent) PMID 30263981 ↗

paper compared with one of 60 (2 per cent) in the control group (P < 0·001). PMID 30263981 ↗

Publications

• Results Stockmann M, Vondran FWR, Fahrner R, Tautenhahn HM, Mittler J, Bektas H, Malinowski M, Jara M, Klein I, Lock JF; Collaborative Fast-track Liver Study Group. Randomized clinical trial comparing liver resection with and without perioperative assessment of liver function. BJS Open. 2018 Jun 14;2(5):301-309. doi: 10.1002/bjs5.81. eCollection 2018 Sep.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	13C-Methacetin	Diagnostic / imaging agent	2 mg/kg	Intravenous

Indications