drugset / Trial / NCT01785979

Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly

NCT01785979

Phase 3 Withdrawn Lihir Medical Centre
RandomizedParallel-groupOpen-labelTreatment

Summary

This randomized clinical trial will address a complication related to recurrent episodes of malaria in endemic areas - hyper-reactive malarial splenomegaly. We aim to assess the efficacy of chloroquine after prednisone-induction therapy compared to standard treatment of chloroquine alone in the treatment of adult patients with newly diagnosed hyper-reactive malarial splenomegaly.

Timeline

Start
2016-01
Primary completion
2017-02
Completion
2017-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chloroquine Small molecule 300 mg
Subject Prednisone Other / unclassified 0.5 mg/kg