drugset / Trial / NCT01785979
Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly
RandomizedParallel-groupOpen-labelTreatment
Summary
This randomized clinical trial will address a complication related to recurrent episodes of malaria in endemic areas - hyper-reactive malarial splenomegaly. We aim to assess the efficacy of chloroquine after prednisone-induction therapy compared to standard treatment of chloroquine alone in the treatment of adult patients with newly diagnosed hyper-reactive malarial splenomegaly.
Timeline
- Start
- 2016-01
- Primary completion
- 2017-02
- Completion
- 2017-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chloroquine | Small molecule | 300 mg | — |
| Subject | Prednisone | Other / unclassified | 0.5 mg/kg | — |