drugset / Trial / NCT01787357
A Study to Assess Electrocardiogram Results in Healthy Volunteers Receiving Canagliflozin (JNJ-28431754)
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to assess the effect of canagliflozin (JNJ-28431754) on electrocardiogram results (recordings of the electrical activity of the heart) in healthy volunteers after a single therapeutic dose (300 mg) and a single supra-therapeutic dose (4 times higher \[1,200 mg\] than the anticipated therapeutic dose of 300 mg). The safety and tolerability of canagliflozin will also be assessed.
Timeline
- Start
- 2008-06
- Primary completion
- 2008-09
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CANAGLIFLOZIN ANHYDROUS | Small molecule | 300 mg | Oral |
| Subject | CANAGLIFLOZIN ANHYDROUS | Small molecule | 1200 mg | Oral |
| Subject | Moxifloxacin | Small molecule | 400 mg | Oral |
Indications
No indication recorded.