drugset / Trial / NCT01788501
Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease
Non-randomizedParallel-groupOpen-labelPrevention
Summary
This study aims to compare efficacy and safety of tacrolimus/methotrexate with cyclosporine/methotrexate for graft versus host disease prophylaxis in paediatric allogeneic hematopoietic stem cell transplantation patients.
Timeline
- Start
- 2011-11
- Primary completion
- 2017-03-01
- Completion
- 2017-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclosporine | Peptide | 3 mg/kg | Intravenous |
| Subject | Methotrexate | Small molecule | 10 mg/m2 | Intravenous |
| Subject | Tacrolimus | Small molecule | 0.03 mg/kg | Intravenous |