drugset / Trial / NCT01789827

Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy

NCT01789827 ↗

Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

This pilot clinical trial studies aldesleukin imaging in viewing tumor growth in patients with stage IV melanoma receiving ipilimumab or pembrolizumab therapy. Diagnostic procedures, such as single-photon emission computed tomography (SPECT), uses radioactive drugs and a scanner to make detailed pictures of areas inside the body and may be a less invasive way to check for stage IV melanoma. Radioactive drugs, such as technetium Tc 99 hydrazinonicotinamide-tricine-linked interleukin-2, carry radiation directly to cancer cells and may be able to differentiate between tumor growth due to inflammation versus tumor progression in patients with stage IV melanoma receiving therapy.

Timeline

Start
2014-03
Primary completion
2018-06-27
Completion
2018-06-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Technetium Tc 99 Hydrazinonicotinamide-Tricine-linked Interleukin-2 Diagnostic / imaging agent — —

Indications