drugset / Trial / NCT01805817
Comparison of Levonorgestrel Intrauterine System, Copper T Intrauterine Device and Oral Contraceptives on Life Quality
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Oral combined contraceptives(OC) have both progesterone and estrogen inside. Levonorgestrel-releasing intrauterine device(LNG\_IUS) has only progestagen. Copper IUD does not have any hormonal molecule inside. * Hypothesis is OC has more systemic beneficial or side effects than LNG\_IUS or copper IUD. LNG\_IUS has more local effects than copper IUD. * Study reflects the beneficial or side effects of estrogen+progestagen pills and only progestogen inside device.
Timeline
- Start
- 2012-12
- Primary completion
- 2013-12
- Completion
- —
Publications
- Background Haliloglu B, Celik A, Ilter E, Bozkurt S, Ozekici U. Comparison of uterine artery blood flow with levonorgestrel intrauterine system and copper intrauterine device. Contraception. 2011 Jun;83(6):578-81. doi: 10.1016/j.contraception.2010.09.001. Epub 2010 Oct 18.
- Background Sayed GH, Zakherah MS, El-Nashar SA, Shaaban MM. A randomized clinical trial of a levonorgestrel-releasing intrauterine system and a low-dose combined oral contraceptive for fibroid-related menorrhagia. Int J Gynaecol Obstet. 2011 Feb;112(2):126-30. doi: 10.1016/j.ijgo.2010.08.009. Epub 2010 Nov 19.
- Background Mansour D, Gemzell-Danielsson K, Inki P, Jensen JT. Fertility after discontinuation of contraception: a comprehensive review of the literature. Contraception. 2011 Nov;84(5):465-77. doi: 10.1016/j.contraception.2011.04.002. Epub 2011 Jun 8.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Drospirenone/Ethinyl Estradiol | Unknown | — | Oral |
Indications
No indication recorded.