A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients

Phase 1/2 Completed 16 enrolled Augusta University American Heart Association · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

The MACH Trial is a pilot study of 400mg minocycline over five days in acute intracerebral hemorrhage patients. The study will evaluation the safety and efficacy of minocycline in intracerebral hemorrhage patients.

Timeline

Start: 2013-02
Primary completion: 2016-12
Completion: 2016-12

Publications

Fouda AY, Newsome AS, Spellicy S, Waller JL, Zhi W, Hess DC, Ergul A, Edwards DJ, Fagan SC, Switzer JA. Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial. Stroke. 2017 Oct;48(10):2885-2887. doi: 10.1161/STROKEAHA.117.018658. Epub 2017 Sep 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Minocycline	Small molecule	400 mg	Intravenous

A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients

Summary

Timeline

Publications

Drugs

Indications