drugset / Trial / NCT01807702
13C-Pyruvate Breath Test
NaSingle-groupOpen-labelHealth-services research
Summary
The purpose of the test is to measure an enzyme called pyruvate. Subjects will fast for 12 hours and then undergo a breath test, have blood drawn, and cells from the inside of the mouth collected over a 12 hour period. The tests will be repeated at least a week later and subjects receive a dose of dichloroacetate (DCA)
Timeline
- Start
- 2013-03
- Primary completion
- 2013-07
- Completion
- 2013-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dichloroacetate | Small molecule | 25 mg | — |
| Subject | Hyperpolarized 13C-Pyruvate | Diagnostic / imaging agent | 25 mg | — |
| Background | 13C-lactate | Unknown | — | — |
Indications
No indication recorded.